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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
19.09
Human Site:
S252
Identified Species:
32.31
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S252
P
R
N
A
A
R
I
S
E
K
R
K
E
Y
M
Chimpanzee
Pan troglodytes
XP_509445
540
59236
C95
R
K
E
Y
M
D
A
C
G
E
A
N
N
Q
N
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S252
P
R
N
A
A
R
I
S
E
K
R
K
E
Y
M
Dog
Lupus familis
XP_534658
709
78944
S252
P
R
N
A
A
R
I
S
E
K
R
K
E
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S255
P
R
N
A
A
R
I
S
E
K
R
K
E
Y
M
Rat
Rattus norvegicus
NP_001099399
476
51796
A31
E
C
P
M
P
R
N
A
A
R
I
S
E
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S249
P
R
N
P
A
R
I
S
E
K
R
K
E
F
M
Chicken
Gallus gallus
Q5F3D1
613
68449
N168
Y
G
E
A
S
N
Q
N
F
Q
Q
R
Y
H
A
Frog
Xenopus laevis
Q6DD45
743
82926
N238
P
R
D
Q
A
H
I
N
M
K
R
K
E
F
L
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
A239
C
P
K
P
K
D
M
A
R
I
N
E
K
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
N108
K
Q
I
V
F
R
D
N
P
Q
E
L
M
I
S
Honey Bee
Apis mellifera
XP_001122586
556
62911
T111
L
E
V
W
D
N
D
T
D
S
I
S
Q
S
I
Nematode Worm
Caenorhab. elegans
P34656
453
51815
E8
M
S
D
I
E
I
I
E
E
I
Q
P
V
S
L
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
E181
N
E
K
H
S
L
R
E
C
P
V
A
R
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
100
100
N.A.
100
13.3
N.A.
86.6
6.6
53.3
0
N.A.
6.6
0
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
26.6
N.A.
93.3
46.6
80
26.6
N.A.
26.6
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
36
43
0
8
15
8
0
8
8
0
0
8
% A
% Cys:
8
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
8
15
15
0
8
0
0
0
0
8
0
% D
% Glu:
8
15
15
0
8
0
0
15
43
8
8
8
50
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
15
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
0
8
50
0
0
15
15
0
0
8
8
% I
% Lys:
8
8
15
0
8
0
0
0
0
43
0
43
8
8
8
% K
% Leu:
8
0
0
0
0
8
0
0
0
0
0
8
0
0
22
% L
% Met:
8
0
0
8
8
0
8
0
8
0
0
0
8
0
36
% M
% Asn:
8
0
36
0
0
15
8
22
0
0
8
8
8
0
8
% N
% Pro:
43
8
8
15
8
0
0
0
8
8
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
0
8
0
0
15
15
0
8
8
0
% Q
% Arg:
8
43
0
0
0
50
8
0
8
8
43
8
8
8
8
% R
% Ser:
0
8
0
0
15
0
0
36
0
8
0
15
0
15
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
8
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _